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In addition, some cancer drugs cause DNA damage.
Source: https://www.chiangraitimes.com/health/brca2-and-cancer-understanding/
It uses cell cycle, transcriptional regulation and DNA damage response biology to develop medicines for cancer and other proliferative diseases.
Lycopene can help prevent that initial DNA damage, reducing the load that the body has to bear and the repairs that have to be made."
Source: https://www.chroniclelive.co.uk/news/health/michael-mosley-food-prevent-cancer-27816797
They also hypothesize that combining etoposide with inhibitors of nucleotide synthesis processes could potentiate the effect of the drug by preventing the repair of DNA damage and ensuring cancer cells self-destruct correctly.
Source: https://phys.org/news/2023-05-dna-antioxidant-enzymes.html